Post-graduate Course 04. Managing children with drug-resistant tuberculosis: a practical approach

Thursday, 31 October 2013, 9:00 – 17:00, Room: 341

44th Union World Conference on Lung Health, 30 October – 3 November 2013, Paris, France


Despite some advances in expanding access to effective treatment for drug-resistant tuberculosis (DR-TB), children remain largely neglected. Diagnosis of DR-TB in children is perceived to be challenging and few providers have experience managing children with DR-TB. This course aimed to provide workers with practical advice and guidance to manage children with DR-TB. It addressed diagnosis, prevention, treatment, delivery of medication doses, management of adverse events, and approaches to the programmatic management of DR-TB in children.

This course was aimed at any health care worker who may manage children with drug-resistant tuberculosis. The course’s strong clinical and practical components were of use to those working in the community, clinic, hospital, or TB programme.


1. Overview of the epidemiology of DR-TB in children
Soumya Swaminathan (India) [Download Slides Here]

2. Family-centered approach: framework for managing children exposed to DR-TB
Jeffrey Starke (USA) [Download Slides Here]

3. Diagnosis of DR-TB disease in children
Carlos Perez-Velez (USA) [Download Slides Here]

4. Treatment of DR-TB disease in children and preventive therapy for children exposed to DR-TB
H. Simon Schaaf (South Africa) [Download Slides Here]

5. Pharmacokinetics of second-line TB drugs
Helen McIlleron (South Africa) [Download Slides Here]

6. Practical approach to weight-based dosing
Carole Zen Ruffinen (Switzerland) [Download Slides Here]

7. Co-morbidities, monitoring and adverse events, nutritional support and adherence
Jennifer Furin (USA) [Download Slides Here]

8. Program monitoring and evaluation, including registers and forms
Florian Marx (Germany) [Download Slides Here]

9. Implementing a protocol to evaluate child contacts of DR-TB patients
Farhana Amanullah (Pakistan) [Download Slides Here]

10. Managing DR-TB in pregnancy, mothers and newborns
James Seddon (UK) [Download Slides Here]

CoordinatorsMercedes Becerra (USA), James Seddon (UK)

Chairs: Mercedes Becerra (USA), James Seddon (UK)

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